Bacteriophage
Essentially, they are nonliving biological entities consisting of DNA or RNA embedded within a protein capsid. They are obligate bacterial parasites, meaning they cannot reproduce independently, so they require a host bacterium for survival.
Despite their simplicity, they are highly diverse and have several classification criteria. Phages exhibit four distinct cycles they can use to infect their host bacteria: lytic, lysogenic, pseudolysogenic, and chronic infection.
The general description of these phages is as follows: the genetic material is contained within a protein coat or capsid; this capsid is connected to the tail via the collar. This tail, at its most distal end, is in contact with tail fibers with spikes that recognize docking sites on bacterial cell surface receptors.
Product Efficacy:
1.Phage therapy has a narrow spectrum of action, and its effect can be limited to a single species, or even a single strain within a species.. Therefore, the natural commensal microbiota in the gastrointestinal tract of humans and animals is not destroyed.
2. Bacteriophages consist of proteins and nucleic acids, so they are non-toxic. Low impact on the body.
3. Lower doses. Phages can increase in number depending on the number of target bacteria, so it is not necessary to use the same dose as the antibiotics; in this case, the dose of phages used can be lower than that of the antibiotics Since phages' propagation depends on bacteria, it only occurs where the bacteria appear, at the site of infection, thus limiting the phages' activity in both quantity and space. In contrast, antibiotics do not concentrate at the site of infection, but travel throughout the body.
4. Ability to act against bacterial biofilms,Phage preparations can be adaptable; a single phage type or multiple phage types can be used. The latter is a preparation called a cocktail, and they are the most commonly used preparations due to their broader spectrum of antibacterial action.
5. The development process of antibiotics can take many years and require a lot of money for clinical testing; Phage detection, isolation, and characterization are rapid processes, and their costs are relatively low. It should also be noted that, as technological improvements continue, the cost of phage purification will decrease.
Package:
Packe:1 kg aluminum foil bag
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